Scleroderma History


Table of Contents

Scleroderma History

The term, scleroderma was coined by Giovambattista Fantonetti in 1836. He used the term to describe a patient that had dark, leather-like skin and reduced joint mobility from tightening of the skin. Purging, ingesting dulcamara (bittersweet), and bathing in cicuta water (hemlock) softened her skin.Jun 24, 2020

How did your scleroderma start?

Doctors don’t know exactly what causes this process to begin, but the body’s immune system appears to play a role. Most likely, scleroderma is caused by a combination of factors, including immune system problems, genetics and environmental triggers.

Where was scleroderma discovered?

According to, Hippocrates was the first to describe the illness as thickened skin. The first detailed description of the disease was by an Italian doctor named Carlo Curzio in the mid 1700s.

Who discovered systemic scleroderma?

About three per 100,000 people per year develop the systemic form. The condition most often begins in middle age. Women are more often affected than men. Scleroderma symptoms were first described in 1753 by Carlo Curzio and then well documented in 1842.

Is scleroderma considered a rare disease?

Scleroderma is a chronic but rare autoimmune disease in which normal tissue is replaced with thick tissue with extra collagen. Although it most often affects the skin, scleroderma also can affect many other parts of the body.

How did you know scleroderma?

Symptoms of scleroderma may include: Thickening and swelling of the fingers. Pale fingers that may become numb and tingle when exposed to cold or stress, known as Raynaud’s phenomenon. Joint pain.

Is scleroderma always fatal?

It is the most fatal of all the rheumatologic diseases. Systemic scleroderma is very unpredictable although most cases can be classified into one of four different general patterns of disease (see Classification).

What did Bob Saget sister have?

Does scleroderma skip a generation?

Genetics plays a role in the disease, but it is not passed on from parents to children, and it’s rare for immediate family members of those with scleroderma to get it. It is common for family members, however, to have other autoimmune diseases such as thyroid disease, rheumatoid arthritis or lupus.

When was scleroderma discovered?

Not Only Skin Deep

In the US, the first account of Scleroderma was recorded in 1869 by Abraham B. Arnold. A 52-year-old man developed a cough followed by skin hardening on his hands and feet. Hydrotherapeutics resolved hardening of skin on the arms but not the hands and the feet.

Can scleroderma be reversed?

Currently, there’s no cure for scleroderma, so doctors will find the treatments that work best to decrease the severity of the specific symptoms and manage or prevent additional complications.

What is the life expectancy of a person with scleroderma?

People who have localized scleroderma may live an uninterrupted life with only minor symptom experiences and management. On the other hand, those diagnosed with an advanced and systemic version of the disease have a prognosis of anywhere from three to 15 years.

What is the difference between systemic sclerosis and scleroderma?

The word “scleroderma” means hard skin in Greek, and the condition is characterized by the buildup of scar tissue (fibrosis) in the skin and other organs. The condition is also called systemic sclerosis because the fibrosis can affect organs other than the skin.

Is scleroderma worse than lupus?

Worse than in rheumatoid arthritis or lupus. Patients with systemic sclerosis (SSc) have worse health-related quality of life than patients with other systemic rheumatic diseases such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), a Korean study found.

Does scleroderma make you look younger?

As the result, the severity of wrinkles, texture and pores were significantly lower in SSc patients than control subjects. Among them, wrinkles showed better correlation with skin thickness score. Therefore, increased amount of collagen in scleroderma skin may directly affect wrinkles.

What foods should be avoided with scleroderma?

REFLUX/HEARTBURN: eat small frequent meals to avoid overfilling your stomach; avoid eating within 2-3 hours of bedtime; avoid foods that may aggravate symptoms such as citrus fruits, tomato products, greasy fried foods, coffee, garlic, onions, peppermint, gas-producing foods (such as raw peppers, beans, broccoli, raw …

What can scleroderma be mistaken for?

However, similar features of hard and thick skin can be seen in other conditions which are often referred to as scleroderma mimics. These mimics include eosinophilic fasciitis, nephrogenic systemic fibrosis, scleromyxedema, and scleredema among others.

What does scleroderma rash look like?

The patches of hardened skin can be lighter or darker than your natural skin color. Some people develop violet-colored skin, which means that the scleroderma is active and expanding. This patient has darker and lighter (white) areas that are hard to the touch.

Is scleroderma often misdiagnosed?

Misdiagnosis is very common with scleroderma patients because its symptoms are quite common.

Can scleroderma be caused by stress?

We agree that susceptibility, progression and clinical presentation of scleroderma are influenced by a strong interplay of several factors, of which one is psychosocial stress (25). Our preliminary findings further suggest that mechanical stress is involved in the onset, continuation and exacerbation of scleroderma.

Can you drink coffee with scleroderma?

Reduce pasta and bread, carbohydrates, starch, sugar consumption. Do not drink alcohol or caffeine.

What happens if scleroderma is left untreated?

Scleroderma causes a restrictive ventilatory defect (small lungs) secondary to an inflammatory process in the lung alveoli (air sacs). This process, left untreated, leads to fibrosis of the lung tissue (a fibrosing alveolitis) that interferes with normal gas exchange from the air to the blood.

What actor has scleroderma?

As Bob Saget is remembered by his friends and co-stars, one memory that stands out is his commitment to finding a cure for scleroderma, a rare disease for which Saget was the most high-profile advocate. Saget, 65, died unexpectedly Jan. 9, on what would have been the 75th birthday of his late sister, Gay.

How long did Bob Saget’s sister live with scleroderma?

She was 44 in 1992 when she was diagnosed with systemic scleroderma, a disease that strikes mostly women in the prime of their lives. She had been living in Bucks County, Pennsylvania, but moved back to Los Angeles to be with my parents as they sought medical care for her. Two years later, she passed away.

What religion is Bob Saget?

Saget was born in Philadelphia, Pennsylvania, on May 17, 1956, to a Jewish family.

Can you have scleroderma without skin involvement?

It is possible to have systemic sclerosis without skin thickening (sine scleroderma), which is when there are internal organ manifestations without skin findings, but this is very rare.

Can I get a Covid vaccine if I have scleroderma?

To our knowledge, this is the first large study that details experiences with COVID-19 vaccines in systemic sclerosis. Vaccination was safe in this group with no serious adverse events, a side-effect profile similar to that seen in other populations, and a low rate of reported systemic sclerosis flare.

Is there a blood test for scleroderma?

A blood test alone cannot diagnose scleroderma. Depending on the clinical situation, additional tests may be done, such as: Pulmonary function tests or breathing tests to measure how well the lungs are working. CT chest scan may also be ordered to evaluate the extent of lung involvement.

What causes Scleredema?

Febrile illness with streptococcal infections [8, 9] : An upper respiratory tract infection (typically pharyngitis) is the most common cause of scleredema in patients with type 1 scleredema. Scleredema following scabies infestation, as a result of superinfection with Streptococcus, has been reported.

What does crest syndrome mean?

CREST (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) syndrome is a member of the heterogeneous group of sclerodermas, and its name is an acronym for the cardinal clinical features of the syndrome.

What are the pathological changes associated with scleroderma?

The clinical and pathologic manifestations result from three distinct processes: 1) severe fibroproliferative vascular lesions of small arteries and arterioles, 2) excessive and often progressive deposition of collagen and other extracellular matrix (ECM) macromolecules in skin and various internal organs, and 3) …

Can you live a full life with scleroderma?

Many people have a good scleroderma prognosis – they do not die of the disease and live a full and productive life. However, some people do die from scleroderma, for example those with severe lung, heart or kidney involvement.

Can scleroderma stay mild?

In many patients, it remains being mild and does not progress. In general, the more skin that is involved, the more severe the case of scleroderma. Learn more about the different types of Scleroderma.

Does exercise help scleroderma?

Exercising safely with scleroderma

Most studies have proven that aerobic exercise, or aerobic exercise combined with resistance exercise, improves exercise tolerance, aerobic capacity, walking distance, muscle strength and function as well as health-related quality of life.

Is scleroderma a death sentence?

With proper management and constant consultation, patients with scleroderma would live to the fullest, a professor of medicine and consultant rheumatologist at Lagos State University Teaching Hospital (LASUTH), Femi Adelowo has said.

How do you stop scleroderma progression?

Lifestyle and home remedies
  1. Stay active. Exercise keeps your body flexible, improves circulation and relieves stiffness. …
  2. Protect your skin. Take good care of dry or stiff skin by using lotion and sunscreen regularly. …
  3. Don’t smoke. …
  4. Manage heartburn. …
  5. Protect yourself from the cold.

Can scleroderma be asymptomatic?

Patients with significant internal organ involvement are often asymptomatic until the late stages of systemic sclerosis; therefore, routine monitoring for underlying disease is essential after the initial diagnosis.

Is brain fog a symptom of scleroderma?

“I didn’t realize, I didn’t understand a lot of the difficulties,” he said. “One of the things I didn’t realize was her having trouble with names,” he said of the brain fog many scleroderma patients describe as the disease begins to affect brain function.

How do you fight scleroderma fatigue?

Try to Get Some Exercise

People often say they don’t exercise because they feel fatigued. This creates a vicious cycle. Fatigue gets worse because of a lack of exercise and people avoid exercise because of fatigue. Taking a short walk instead of lying down the next time you’re feeling tired may actually help.

Can people with scleroderma have kids?

With the right prenatal care, many women with scleroderma can have healthy pregnancies and babies.

Does scleroderma cause weight gain?

Acute localized scleroderma (morphea) can present as severe generalized oedema with rapid weight gain and oliguria.

About the author

Add Comment

By Admin

Your sidebar area is currently empty. Hurry up and add some widgets.