Study: DDT Exposure Linked to Obesity Across Generations


Study: DDT Exposure Linked to Obesity Across Generations

The study found that the risk of obesity in young adult granddaughters was two to three times greater when their (not overweight) grandmothers had higher levels of o,p’-DDT a contaminant of commercial DDT in their blood during or just after pregnancy.14 Apr 2021

Can DDT be passed on to offspring?

Combined observations indicate that the LD DDT-induced transgenerational obesity and associated disease is predominately transmitted through the female (egg) germline, but specific diseases (for example, kidney) are also transmitted through the male (sperm) germline.

How did DDT affect people in the past?

Human health effects from DDT at low environmental doses are unknown. Following exposure to high doses, human symptoms can include vomiting, tremors or shakiness, and seizures. Laboratory animal studies showed effects on the liver and reproduction. DDT is considered a possible human carcinogen.

What is the long term affect for using DDT?

Our results suggest that chronic occupational exposure to DDT is associated with a permanent decline in neurobehavioural functioning and an increase of neuropsychological and psychiatric symptoms. The amount of decline was directly associated with years of DDT application.

Which diseases did DDT affect?

Development of DDT

It was initially used with great effect to combat malaria, typhus, and the other insect-borne human diseases among both military and civilian populations.

How did DDT affect animals?

DDT affects the central nervous system of insects and other animals. This results in hyperactivity, paralysis and death. DDT also affects eggshell production in birds and the endocrine system of most animals. DDT has a very high tenancy towards biomagnification.

What are the effects of DDT on animals?

Laboratory animals exposed to DDT develop hyperexcitabiliy, tremors, incoordination, and convulsions (1). See boxes on Toxicity Category and LD50/LC50. Animals given potentially fatal doses of DDT develop liver lesions and those given DDT over a long period of time develop liver changes (1).

What are the effects of DDT in both humans and animals?

Low to moderate exposure (10mg/kg) may result in nausea, diarrhea, irritation of eyes, nose or throat, while higher doses (16mg/kg) can lead to tremors and convulsions. In experimental animals, such as mice, rats, and dogs, DDT has shown to cause chronic effects on the nervous system, liver, kidneys, and immune system.

What is DDT and why is it harmful?

DDT is considered to be an endocrine-disrupting chemical, or an EDC, a category of chemicals that researchers find particularly worrisome because of evidence that they alter and disrupt hormones important to good health, including reproductive health, as well as neurological and immune functions.

Is DDT fat soluble?

Since DDT is lipid soluble and accumulates in adipose tissue it could have a role in lipid metabolism.

Is DDT a neurotoxin?

DDT is found to be one of those neurotoxins that are potentially harmful to neurons during growth and development [15, 25, 26]. Exposure of fetal and neonatal neurons to DDT and other neurotoxins may act through maternal routes, i.e., either by placental or milk feeding [1, 16, 17].

How are we exposed to DDT?

Exposure to DDT in people likely occurs from eating foods, including meat, fish, and dairy products. DDT exposure can occur by eating, breathing, or touching products contaminated with DDT. DDT can convert into DDE, and both persist in body and environment.

Does DDT cause malaria?

DDT is used in IRS by spraying indoor surfaces with a coating of DDT. This residual coating prevents malaria transmission as a spatial repellent or contact irritant or by killing mosquitoes (indicating more than one mode of action), effectively preventing or interrupting transmission (Grieco et al.

Does DDT cause polio?

Most people today know that spraying DDT will not prevent polio, and can actually harm one’s health. Rachel Carson’s Silent Spring (1962) exposed the hazards of commonly-used pesticides, and the chemical was mostly banned in the early 1970s.

How does DDT move through the environment?

DDT, DDE and DDD may also enter the air when they evaporate from contaminated water and soil. DDT, DDE, and DDD in the air will then be deposited on land or surface water. This cycle of evaporation and deposition may be repeated many times. As a result, DDT, DDE, and DDD can be carried long distances in the atmosphere.

What is uniquely problematic about DDT?

What is uniquely problematic about DDT and other chlorinated hydrocarbons? The issue with DDT and chlorinated hydrocarbons is that they are fat-soluble. The toxins stick to organs in the body and can have a lasting effect, but doesn’t show immediately.

Does DDT cause air pollution?

Answer: (4) Air, water and soil

Spraying of DDT chemicals leads to the pollution of the air, soil and water. Soil is the main polluting part when DDT is sprayed to the crops. Few drops will anyhow spill into the ground which causes soil to get polluted.

How do pesticides affect humans?

Pesticides and human health:

Pesticides can cause short-term adverse health effects, called acute effects, as well as chronic adverse effects that can occur months or years after exposure. Examples of acute health effects include stinging eyes, rashes, blisters, blindness, nausea, dizziness, diarrhea and death.

How does the body get rid of DDT?

Here are some simple tips to do so:
  1. Add dulse to your diet. …
  2. Red Clover helps clean the lymphatic system and help the body’s ability to clean DDT out of the system. …
  3. Eat wild blueberries. …
  4. Eat parsley to pull out toxins from your organs and small intestines!

Is DDT is biodegradable or nonbiodegradable?

DDT (Dichlorodiphenyltrichloroethane) is non biodegradable pesticide i.e. it cannot be degraded by the action of microbes.

Is DDT biodegradable?

DDT is harm to all biota of the planet as it is non-biodegradable, and tends to become more concentrated as it moves up the food chain. It is a fat-soluble chemical, and accumulates in the fat deposits of the body.

Is DDT a non degradable pollutant?

DDT, plastics, polythene, bags, insecticides, pesticides, mercury, lead, arsenic, metal articles like aluminum cans, synthetic fibres, glass objects, iron products and silver foils are non-biodegradable pollutants.

Can DDT cause neuropathy?

Chronic low dose pesticide exposure could lead to delayed peripheral neuropathy as well as systemic (skin, eyes and lungs) complications.

Is DDT an endocrine disruptor?

DDT is considered an “endocrine disruptor,” which means it’s capable of interfering with hormone activity in the body. In past studies, Cohn’s team has found that women’s DDT levels during pregnancy in the 1960s might affect the long-term health of their kids.

Is DDT banned worldwide?

Banned for agricultural uses worldwide by the 2001 Stockholm Convention on Persistent Organic Pollutants, the use of DDT is still permitted in small quantities in countries that need it, with support mobilized for the transition to safer and more effective alternatives.

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