What is a surrogate marker in medicine?
A “surrogate marker” can be defined as “ …a laboratory measurement or physical sign that is used in therapeutic trials as a substitute for a clinically meaningful endpoint that is a direct measure of how a patient feels, functions, or survives and is expected to predict the effect of the therapy.”5 The primary …
Is PFS a surrogate endpoint?
They reported a strong correlation between the two endpoints at the individual level, but not at the trial level. [1] Based on these observations they concluded that PFS is not an adequate surrogate endpoint for OS in the initial treatment of ovarian cancer.
What are the endpoints of a clinical trial?
The endpoints of a clinical trial are usually included in the study objectives. Some examples of endpoints are survival, improvements in quality of life, relief of symptoms, and disappearance of the tumor.
What is a secondary endpoint?
Secondary endpoints are additional endpoints, preferably also pre-specified, for which the trial may not be powered.
What is an exploratory endpoint?
Exploratory endpoints may include clinically important events that are expected to occur too infrequently to show a treatment effect or endpoints that for other reasons are thought to be less likely to show an effect but are included to explore new hypotheses.
What is a clinical endpoint study?
An endpoint is the primary outcome that is being measured by a clinical trial. A cancer drug, for example, might use survival as an endpoint, comparing the five-year survival rate of patients using an experimental therapy against the five-year survival rate of patients using another treatment or a placebo.
How does an endpoint work?
Simply put, an endpoint is one end of a communication channel. When an API interacts with another system, the touchpoints of this communication are considered endpoints. For APIs, an endpoint can include a URL of a server or service. The place that APIs send requests and where the resource lives, is called an endpoint.
How do you create an endpoint?
Create your own REST API endpoint
- Introduction. The File and directory structure.
- Plugin files. SwagBannerApi.php. Components/Api/Resource/Banner.php. Controllers/Api/Banner.
- Test the API. GET. GET(List) PUT. POST. DELETE.
- Download plugin.
What is Tanium endpoint?
Tanium Endpoint Management allows organizations to manage endpoints from a single platform, offering new levels of control, visibility and efficiency across operations and security.
Why is Tanium used?
Tanium is manifestly an endpoint management tool. It excels at managing endpoints with unparalleled speed and scale. ServiceNow is a cloud-based service management platform. It is often used for asset and configuration management.
Who uses Tanium?
Tanium is most often used by companies with >10000 employees and >1000M dollars in revenue. Our data for Tanium usage goes back as far as 3 years and 9 months. If you’re interested in the companies that use Tanium, you may want to check out Trend Micro and Rapid7 as well.
What is Tanium process?
The Tanium Client is a service installed on endpoint computers that discovers and reports data from those endpoints. You can monitor client health using Client Management. …
What is Tanium server?
The Tanium Server is the server that communicates with Tanium™ Clients, other Tanium Core Platform servers, and the content.tanium.com servers that host Tanium content packs. Tanium Clients communicate with the Tanium Server directly or through a Tanium Zone Server that acts as a proxy.
Is Tanium an antivirus?
Antivirus Management With Tanium Enforce, leverage native AV capabilities by completely managing and configuring Defender across the organization.
Can Tanium replace SCCM?
While you could replace SCCM with Tanium, it’s certainly not recommended.
What is better than SCCM?
SCCM Alternatives and Competitors
- Ansible.
- BigFix.
- Quest KACE Systems Management.
- Ivanti Patch for Windows.
- Tanium. 4.0.
- ManageEngine Desktop Central. 4.4.
Will intune replace SCCM?
Microsoft Intune is solely a cloud technology. It is also known as cloud variant of SCCM but it is NOT equivalent to SCCM.
Is Tanium cloud based?
Tanium™ as a Service (TaaS) is the full functionality of the Tanium platform delivered as a fully-managed, cloud-based service, with zero customer infrastructure required.
Is Tanium an EDR?
Tanium Threat Response introduces real-time alerting, allowing security teams to detect a broad range of attacks using custom or built-in intelligence from Tanium’s EDR team. And Operations teams will be able to remediate incidents on one or more endpoints across the enterprise in seconds.
Is Tanium a good company?
Tanium regularly ranks among the top workplaces in technology. In 2020, the company has already been ranked in the top 10 on two Best Workplaces lists: 100 Best Places to Work in Technology and 100 Best Places to Work in the Bay Area. In 2019, it ranked ninth on the Forbes Cloud 100 list.
What is Endpoint monitoring?
In practical terms, endpoint monitoring is the collection, aggregation, and analysis of endpoint behaviours across an organisation’s environment to identify signs of malicious activity.