What is single blind or double-blind peer review?
Single-blind peer review is the traditional method of review. In it, reviewers know the identity of authors, but authors don’t know the identity of reviewers. (In double-blind review, neither reviewers nor authors know who the other party is.
What is a blind review for a peer reviewed journal?
In single-blind peer review, the authors do not know who the reviewers are. The reviewers know who the authors are. In double-blind peer review, neither authors nor reviewers know each other’s names. Single-blind peer review is the traditional model. However, both models exist to eliminate bias in peer review.
What does double-blind peer review mean?
This journal uses double-blind review, which means that both the reviewer and author identities are concealed from the reviewers, and vice versa, throughout the review process. To facilitate this, authors need to ensure that their manuscripts are prepared in a way that does not give away their identity.
What does double-blind mean?
(DUH-bul-blind STUH-dee) A type of clinical trial in which neither the participants nor the researcher knows which treatment or intervention participants are receiving until the clinical trial is over.
What is the purpose of a double blind study?
The best and most reliable form of research is the double-blind, placebo-controlled study. The purpose of this kind of study is to eliminate the power of suggestion. The double-blind study keeps both doctors and participants in the dark as to who is receiving which treatment.
What happens in a double blind trial?
A double blind trial is a trial where neither the researchers nor the patients know what they are getting. The computer gives each patient a code number. And the code numbers are then allocated to the treatment groups. Your treatment arrives with your code number on it.
Is a double blind experiment used to increase the placebo effect?
A double-blind experiment is used to increase the placebo effect. The statement is false. Double blinding is used to decrease the placebo effect. Using a systematic sample guarantees that members of each group within a population will be sampled.
Why is a double blind trial more reliable?
Double-blind trials are seen as the most reliable type of study because they involve neither the participant nor the doctor knowing who has received what treatment. The aim of this is to minimize the placebo effect and minimize bias.
Are double blind studies ethical?
The difficulty with the balanced placebo design is an ethical one—it involves deceiving participants and violating the principle of informed consent. The fact that such studies cannot be done ethically, however, leaves the problem of effectively controlling for expectancies unresolved.
How do you double blind an experiment?
A double blind experiment requires that both researchers and test subjects are unaware of who is receiving the treatment and who is receiving the placebo. If only one group is unaware, it is a single blind experiment. If both groups are aware, the experiment is not blinded.
What is a double dummy trial?
A technique for retaining the blinding of a clinical trial, where the two treatments cannot be made identical.
What is a triple dummy study design?
Triple-blind (i.e., triple-masking) studies are randomized experiments in which the treatment or intervention is unknown to (a) the research participant, (b) the individual(s) who administer the treatment or intervention, and (c) the individual(s) who assess the outcomes.
What is a parallel group study?
A parallel group design is an experimental study design in which each subject is randomized to one of two or more distinct treatment/intervention groups. Those who are assigned to the same treatment are referred to as a treatment group.
What is a treat to target trial?
In treat-to-target trials of insulin therapy, insulin doses are titrated to enable patients to achieve a known and validated target level of glycaemic control.
What is an active controlled trial?
a two-group experimental design in which one group receives the treatment under study and the second group receives a comparable standard treatment. Compare placebo controlled trial. …
How do you titrate long acting insulin?
Titrating Insulin To normalize the FPG with long-acting basal insulin, it is safe to start empirically at 10 units daily or at a low dose of 0.15 U/kg/day. Patients should titrate the dose 2 units at a time every two to three days, based on SMBG, until the FPG is at goal.
Why is Lantus given at night?
giving steady concentrations throughout the day. But for some patients, it doesn’t last the full 24 hours. Morning dosing might be preferred for these patients. That way, Lantus wears off at night when insulin requirements are lower.
When should blood glucose testing be done with BBIT?
Timing of insulin administration should be coordinated with meals and blood glucose testing. o Blood glucose testing should be done within 30 minutes prior to meal, and o Insulin should be administered based on this blood glucose test no more than 30 minutes prior to meals.
What is the max amount of insulin per day?
Patients who require >1 unit/kg/day are considered to have insulin resistance, and those requiring >2 units/kg/day have severe resistance (3). Alternatively, a total daily insulin dose of >200 units is commonly considered to be evidence of severe insulin resistance.
What is the 500 rule in diabetes?
Use the 500 Rule to estimate insulin-to-carb ratio: 500/TDD = number of carb grams covered by a unit of insulin. Example: 500/50=10; 1unit of insulin will cover about 10 grams of carbohydrate.
How much does 1 unit of insulin bring down blood sugar?
One unit of insulin should cause your blood sugar level to drop 30 to 50 mg per dL, but you may need more insulin to get the same effect.
Is 100 units of Lantus too much?
There is no maximum dose of glargine per se, although at doses >100 units, I usually prescribe this agent b.i.d. In addition, we are finding that in some patients, Lantus seems to last only 12-18 hours, so that splitting the dose to 80 units in the morning and 30 units at bedtime would likely improve his morning/ …
Is 80 units of Lantus too much?
It is possible that the “maximum” of 50 units is derived from the technical limitations of the 1/2 mL syringe. The Lantus SoloStar disposable pen has a maximum “dial-able” dose of 80 units. Aside from this technical maximum, there is no mention of a maximum dose in the package insert.
What happens if you take too much Lantus?
If you have taken too much Lantus, call your local Poison Control Center or seek emergency medical attention right away. Overdose can occur if you use too much Lantus or if you use the right amount of Lantus but eat less than usual or exercise more than usual. Lantus overdose can cause hypoglycemia (low blood sugar).
What is the maximum amount of Lantus per day?
Dosage for type 2 diabetes The maximum starting dose of Lantus is 10 units a day. Lantus is typically taken once a day, not twice a day. The drug is given as an injection just under your skin (a subcutaneous injection).
Can you take Lantus 2 times a day?
Because of its long duration of action insulin glargine is usually prescribed once daily. However, several reports have shown that the administration of insulin glargine once daily is not enough to achieve adequate glucose control in some patients requiring a twice daily dosing [2], [3], [4], [5], [6], [7], [8], [9].
